Clinical Research

Tools to study the immune system's key role in cardiovascular disease.

Inflammation mediated by the secretion of cytokines such as TNF, IFN-γ, and IL-2 has been shown to be a contributing factor to congestive heart failure, atherosclerosis, and transplant rejection. Th17 (IL-17 secreting T cells) may also contribute to cardiovascular disease. The scavenger receptor, CD36, is reported to be involved in vascular cell inflammation and atherosclerosis. To support this evolving area of research, BD Biosciences has tools such as Cytometeric Bead Arrays (CBA kits) for the measurement of multiple cytokines within a single sample, as well as antibodies and panels for the phenotyping of infiltrating immune cells.