Bioprocessing

Pioneering Peptones For Biopharmaceutical Production

The use of BD peptones in bioprocessing applications can significantly improve yields when compared to serum-supplemented media while meeting stringent regulatory requirements.

BD Biosciences–Advanced Bioprocessing plants are ISO 9001 Certified and are operated in accordance with cGMP manufacturing practices. We also provide the biopharmaceutical industry comprehensive documentation, including raw material origin, manufacturing change control and Drug Master Files (DMF) for key products.


Animal-Free Peptones and Yeast Extracts

Robust manufacturing processes, rigorous quality control procedures, and stringent raw material sourcing policies enable consistent performance and safety. BD TC Yeastolate, Yeast Extract, Soytone and Phytone™ products offer a range of optimized nutritional choices to enhance production in both bacterial fermentation and cell culture applications.

Animal Origin Peptones

Meat Peptones

Meat peptones are proteins from animal sources that have been hydrolyzed, or broken down, into amino acids and other components. Meat peptones can be tailored to specific nutritive needs of microorganisms by controlling the quality and origin of the protein, the quality and source of the enzyme used to digest the protein, and the methods used for hydrolysis, concentration and drying the peptone.

Casein and Whey Peptones

Casein and whey peptones are hydrolysates of bovine milk proteins. Milk is a complex material, consisting of water, lactose, lipids, salts and proteins. Casein (80%) and whey (20%) are the fundamental protein components in milk. Casein peptones are manufactured by either acid or enzymatic hydrolysis.

The soluble supernatant material separated from milk after casein precipitates is whey, also called milk plasma. Whey contains the lactalbumin and lactoglobulin proteins and is a byproduct of casein production. Whey protein concentrates and isolates are recovered using various separation technologies such as ion exchange and filtration; lactalbumin is recovered by heat denaturing and then separation. Whey peptones are manufactured using the process of enzymatic hdrolysis on the proteins isolated from whey. The whey peptones contain free amino acids and peptides, as well as carbohydrates, vitamins, and minerals.